Diabetes is one of the world's most dangerous and fastest-growing afflictions. According to the International Diabetes Federation, 366 million people around the globe suffered from this devastating illness in 2011, and diabetes has cost the U.S. health care system hundreds of billions of dollars annually in recent years. Leading big pharma companies have reaped windfalls by developing drugs to treat this epidemic, but treatment and public awareness haven't slowed down its advance across the globe.

The future could be even more menacing -- but for investors, taking advantage of these global health trends now could bring in a huge reward in the long term. Let's take a look at three eye-opening statistics concerning diabetes' future -- and dive into what you can do today to maximize your portfolio's returns tomorrow.

1. 552 million
552 million is the number of people worldwide that the IDF expects to suffer from diabetes by the year 2030, an increase of more than 50% over 2011's total.


The huge increase in diabetes has been fueled by a number of factors, from urbanization to changing diets and the rise of sedentary lifestyles. Type 2 diabetes in particular has erupted, representing more than 90% of total diabetes cases.

It's not just a problem in advanced economies; if anything, diabetes has hit the developing world far harder than it has the earth's richest nations. According to the IDF, 80% of total diabetes cases across the globe stem from "low- and middle-income countries," many outside of Europe and North America. Asia has become a hotbed of the disease with some of the most populous countries in the world experiencing massive booms in both middle class populations and urbanization.

Those trends have turned several leading emerging markets -- including China, India, and Indonesia -- into tomorrow's hardest-hit diabetes markets.

2. 129.7 million
The IDF expects 129.7 million Chinese citizens between the ages of 20 and 79 to have diabetes by the year 2030, more than 20% of the global total. The organization expects India to have another 101.2 million diabetic citizens by that year, and the two countries far outstrip the United States' projections of just 29.6 million diabetes patients by that year.

Already in the present China has emerged as a hotspot for diabetes. Pharmaceutical firm Novo Nordisk estimated the total Chinese market at more than 93 million patients last year. Novo has capitalized by taking a dominant share of that growing diabetes market, carving out a 37% market share last year and growing its Chinese sales by 28%. That hasn't helped Novo's stock recently, but this Danish pharmaceutical maker has emerged as a major player in the future of treating diabetes abroad.

India's growth also has captured the attention of leading big pharma firms. Merck has struggled with falling sales lately, but it has taken full advantage of diabetes' growth. The company's lead diabetes drugs, Januvia and Janumet, posted more than $5.6 billion in sales last year and have made inroads into India's sizable market, as well as Brazil, China, and other developing nations. Merck has had to fight off copycat drugs in India with the nation's shaky patent law framework, but if the company can expand its foothold in growing diabetes hotbeds like China and India, Merck will ride this troubling trend to big sales abroad.

3. $58 billion
$58 billion is how large Standard & Poor's last year estimated that the diabetes market worldwide would grow to by 2018. That's an increase of more than 65% over 2012's global diabetes market, which stood at $35 billion. By a comparison, that's larger than the economies of almost 100 nations.

All those dollars have fueled incredible sales at the largest pharmaceutical players in the industry -- and rewarded forward-thinking investors with some hard-earned cash. If S&P's estimate proves true, there'll be much more to gain in the coming years.

Sanofi's success in treating diabetes is a great example of just how lucrative this market can -- and will -- be. Sanofi's Lantus has become a blockbuster star, generating sales of more than $6.6 billion last year at more than 20% sales growth. While Lantus' patent will expire soon, Sanofi's working on a new and improved version of the drug to protect its lucrative diabetes-fighting business.

Diabetes is such a widespread problem and lucrative market that all the big names are getting involved with developing treatments. Johnson & Johnson's recently approved Type 2 diabetes drug Invokana might not be a household name just yet, but this drug could be a future contender among the market's heavyweight medications. Invokana has performed well against Merck's Januvia in clinical trials, and the drug one day could sell $1 billion or more annually.

Diabetes: A growing menace
Diabetes isn't going away. Hundreds of millions already deal with the affliction on a daily basis, and hundreds more will contract the disease in the years to come. As bad as the diabetes epidemic might be, however, there's a silver lining for investors. Making the right investments today could pay off in a big way as big pharma's top companies search for new and improved ways to fight one of the world's worst health problems. It's a chance to fight back against diabetes' reach and make a great profit while you're at it.

The long-term outlook for diabetes may be grim, but the long-term outlook for your portfolio can look a whole lot better if you make the right moves today. Like with improving your physical health, the earlier you start, the better: The Motley Fool's special free report "3 Stocks That Will Help You Retire Rich" names specific investment opportunities that could help you build long-term wealth and help you retire well. The Fool also outlines critical wealth-building strategies that every investor should know. Click here to keep reading.

The article 3 Shocking Numbers on Diabetes' Grim Future originally appeared on Fool.com.

Fool contributor Dan Carroll has no position in any stocks mentioned. The Motley Fool recommends Johnson & Johnson. The Motley Fool owns shares of Johnson & Johnson. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.

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Ralph Allen

This drug will be a block buster with 90 million obese Americans and 80 million diabetics and pre-diabetics. Arena,s new FDA approved diet pill called Belviq just went on the market. Belviq make people more likely to succeed with weight loss since they feel full more quickly and it reduces food cravings. People who take Belviq with diet and exercise were 2 times more likely to lose 5% body weight and 3 times more likely to lose 10% body weight than the people who just did diet and exercise alone. The label states that if you do not lose 5% of your body weight in 12 weeks then consider stopping. Those that do respond in 12 (about 45% of patients) weeks go on to lose over 10% of their body weight in one year. Losing 22 pounds for a 220 pound person is life changing. So 45% of those taking Belviq lose significant amount of weight.
Belviq has a second mode of action to reduce blood sugar which may end up preventing diabetes in many cases. Diabetics and pre-diabetics who took Belviq, REGARDLESS of weight loss, saw their blood sugar numbers drop by double digit percentages. IE HbA1c -0.9 to -1.2 and fasting glucose feel -27. The cost of medications to reduce HbA1c levels exceeds the cost of Belviq. (seeArena's BloomDM phase III trial) These reductions in diabetic symptoms plus the weight loss at the same time makes Belviq a medical bargain.

August 02 2013 at 5:27 PM Report abuse rate up rate down Reply