Bapineuzumab, the potential megablockbuster Alzheimer's treatment, is dead. Not surprisingly, the drug failed another clinical trial, and Pfizer (NYS: PFE) and Johnson & Johnson (NYS: JNJ) have decided to discontinue the phase 3 program.

The winner here? Elan (NYS: ELN) . Sure the biotech still had a stake in bapineuzumab and shares were down more than 12% on the news today before paring those losses a bit. But it could have been worse.

Elan used to own half of bapineuzumab, but sold half of its stake in the drug to Johnson & Johnson. As part of the deal, Johnson & Johnson funded the first $500 million of its share of the development costs and picked up half of the costs beyond that. Johnson & Johnson also invested $885 million in Elan for $8.25 per share, which provided an infusion of cash that helped get its finances in order.


If Elan is a winner, then obviously Johnson & Johnson is the big loser in all this. Part of the attraction to Elan was a side deal that could have put it in the driver's seat to buy Biogen Idec (NAS: BIIB) , but that got thrown out in court. Considering how weak the phase 2 data was, Johnson & Johnson took a big risk that didn't pay off. On the plus side, its stake in Elan is up about 30%, which should help fund some of the development costs.

We can give Pfizer a pass on this one. It inherited bapineuzumab through the acquisition of Wyeth, but the drug was more gravy than a motivating factor for the purchase. Besides finding a sucker to buy some or all of the rights to its half of the drug, there wasn't much Pfizer could do.

Eli Lilly (NYS: LLY) is an innocent bystander in all this, but its stock is down a few points today because it has an Alzheimer's drug, solanezumab, that works in much the same way as bapineuzumab. Any remaining hope in solanezumab seems to be rapidly fading.

Fool analysts think these three Dow stocks are winners. Find out what they are and why the analysts like them so much in the Fool's free report "The 3 Dow Stocks Dividend Investors Need."

The article The Winner of the Bapi Failure originally appeared on Fool.com.

Fool contributor Brian Orelli holds no position in any company mentioned. Click here to see his holdings and a short bio. The Motley Fool owns shares of Johnson & Johnson. Motley Fool newsletter services have recommended buying shares of Pfizer and Johnson & Johnson. Motley Fool newsletter services have recommended creating a diagonal call position in Johnson & Johnson. The Motley Fool has a disclosure policy. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. Try any of our Foolish newsletter services free for 30 days.

Copyright © 1995 - 2012 The Motley Fool, LLC. All rights reserved. The Motley Fool has a disclosure policy.


Increase your money and finance knowledge from home

What are Penny Stocks

The lucrative and dangerous world of penny stocks.

View Course »

Investing in Startups

The lucrative and risky world of startups.

View Course »

Add a Comment

*0 / 3000 Character Maximum