Both retailers will open at 12 a.m. on Thanksgiving night.
In a statement, Macy's CEO Terry Lundgren said the decision was in direct response to shoppers' "eagerness to shop early for great deals."
Meanwhile, in addition to opening its doors at midnight, Target is extending store hours throughout the season.
On Nov. 25, Target stores will be open from midnight to 11 p.m., and on Christmas eve, stores will be open from 7 a.m. to 7 p.m. or 8 p.m., depending on location.
Are you planning to hit the stores at midnight? We want to hear from you. Email us at DFEds@teamaol.com.